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bookmark_borderDaniel Brouse: About the Author

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Q: Any background on membrane .com?

A: In 1994, I started a publishing company with another scientist (low temperature physicist and co-builder of the Ohio States supercomputer). The name of the publishing company is The Philadelphia Spirit Experiment. As the name suggests, it is a scientific experiment in the publishing of arts and science. At the time, domain names were free and the world wide web was 6 months old. We wanted a name that both rhymed and made a good scientific pun — everything passes through the Membrane Domain. The KingArthur.com anti-IQ test launched in 1995.

We were the first record company, fine arts, science, technology, math, and engineering publisher on the web. As such, we were the first to analize web traffic. Our monthly audience is over 300 million. Innovations include: the clickable button on a webpage, MP3 distribution, pay-per-download, free streaming music, the web-based video… and interactive games to save the planet (including a $1,000,000 prize to solve the Anthropogenic Global Warming problem.

My areas of expertise include: musicology, geology, meteorology, anthropology, biology, health & wellness, sociology, security, climate change, physics, finance, economics, statistics, computer science, data science, chaos theory, political science, publishing, logic, and philosophy. In general, my aptitude is in science, technology, engineering, and math.

— Daniel Brouse

bookmark_borderCOVID Immunity: What We Know

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1) Natural Immunity
If you get a moderate to severe case of COVID-19, most people maintain viable antibodies for 90 days and memory T-cells for 5 months. This will likely give you natural immunity to the same strain of COVID for up to 5 months. The resistance to the UK variant is thought to be diminished. The resistance to the South African variant is thought to be none. There is some concern that COVID may erase all or part of your T cells’ memory for other pathogens.

2) Vaccines
You should anticipate that vaccines will give you a very similar immune response as the natural immunity acquired from contracting COVID. It doesn’t matter which vaccine you receive. You should get whatever vaccine you can get and as soon as possible. You should anticipate needing to get vaccinated every 90 days once vaccines are developed for all the different variants.

The message is — we have to stop the community spread and exponential rise in variants WORLDWIDE. Individual countries can not obtain herd immunity.

More Information on COVID-19

bookmark_borderCOVID-19 Testimonial Update — 1 Year Later

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January 19, 2021
Today is my one year anniversary of catching COVID-19.
* 24 hours later I started feeling weird — upset stomach and vertigo. Difficulty in falling to sleep with the “spins”.

* Woke up the next morning feeling like I had a severe hangover — headache, body ache, fatigue.

* 72 hours later I could not get out of bed and went 3 or 4 days without a memory.

* For the next 2 weeks I had severe symptoms including nightmares, night sweats, loss of smell and taste, difficulty breathing, cough, fatigue, muscle aches, and then finally diarrhea.

* On February 9, COVID took my father’s life.

* Over the next several months I noticed a recurring pattern of symptoms that would come in waves.

* On May 15, I was diagnosed with COVID Long Haulers Syndrome. My doctor informed me there was no known treatment.

* August of 2020, I met Dr. Ade Wentzel and debated the cause of long haulers — autoimmune response due to inactive particles of the virus Vs. COVID-19 Induced Secondary Pellagra (CISP). I started the Vitamin stack but was taking the wrong type of B3.

* October 15, 2020 I start taking the right type of B3 — nicotinic acid. Immediately, I was relieved of my severe symptoms.

* January 19, 2021:
I’m doing well. I keep pushing myself too hard and some mild symptoms return. Also, I tried reducing the nicotinic acid to 35mg a day and severe symptoms returned. So, I’m sticking to 400mg/day and trying not to push too hard. I am thinking there must be some serious long term cell damage?

The main mild symptom is GI related. Kind of hard to explain… sort-of a feeling of lack of control… like I might piss or poop my pants (but I don’t). I still get muscle soreness that seems more sore than I should from mild exertion. Of particular concern is my lower back and my kidneys.

I also seem to get partial night sweats. Unlike when I had COVID and got it all over my body, now it just happens to my head or parts of my body (last night it was behind my knees.) It’s weird… similar weirdness with my preexisting peripheral neuropathy. I’ve seen much improvement on the stack with virtually no pain nor pins-and-needles. But, sometimes pins-and-needles show up in parts of some fingers (not the entire hands and feet like before.) So, it seems the NAD+ regulation is not uniform over my entire body.

Overall I’m actually better than I was before getting COVID. However, when I tried reducing the nicotinic acid, I got diarrhea and headaches and fatigue (much more like when I was severe long hauling.) So, I guess I’m being treated but not cured. Now, I wonder if I will ever be cured?

Ade says, “You will be cured.” …and, is helping me tweak the Vitamin Stack.

Original COVID Testimonial

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderDroughts and Rising Sea Levels

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“There has been a 500% increase in the US drought area,” said Al Roker of the Today show while reporting on 2020 being tied for the hottest year.

The Washington Post reports, “Drought is the sleeper weather story you’ll hear more about in 2021.” [1}

“The impact of desertification is intensifying due to climate change, which is reducing the availability of freshwater, fertile soil, and forest and vegetation. As the degraded land loses value, investments in agriculture and rural development decline even more.” — Ban Ki-moonUnited Nations Secretary-General [2}

This doesn’t have to do with drought episodes. It has to do with areas prone to having droughts. As the area of land that is prone to flooding is increasing exponentially, so too is the land prone to severe, long term drought. We make it even worse by pumping ground water out for agriculture. This depletes the aquifers. The result is sinking land and rising sea levels. The depleted fresh water is then intruded by salt water. Salt water intrusion has a severe impact on the world food supply.

So, you have rising seas above and below the land. Compounding the problem — water expands when it gets warmer. About 1/3 of the rise in sea level is due to thermal expansion of water. [Volumetric Thermal Expansion] The warmer sea water also melts sea ice. The ocean doesn’t reflect the energy the way ice does. In fact just he opposite, the ocean absorbs the heat… making the water warmer… melting more sea ice…. and warming the planet. Which melts the land ice, which raises the sea level. A vicious feedback cycle of fresh water depletion and sea level rise has been created.

Climate change is making weather events more extreme and more frequent. More severe droughts, more severe floods, etc. Energy is being added to the system. “Climate change increases the odds of worsening drought in many parts of the United States and the world in the decades ahead. A changing climate can also alter atmospheric rivers (narrow streams of moisture transported in the atmosphere), which can especially disrupt precipitation patterns in the Western United States. Droughts can persist through a “positive feedback,” where very dry soils and diminished plant cover can further suppress rainfall in an already dry area.” [3]

“Risks from desertification are projected to increase due to climate change (high confidence). The combination of pressures coming from climate variability, anthropogenic climate change and desertification will contribute to poverty, food insecurity, and increased disease burden (high confidence).” [4]

1. Drought is the sleeper weather story you’ll hear more about in 2021. (The Washington Post)
2. DESERTIFICaTION (United Nations)
3. Drought and Climate Change (Center for Energy and Climate Solutions)
4. SPECIAL REPORT: Climate Change and Land Desertification (International Panel on Climate Change)

bookmark_borderGood Gut Bacteria

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Your good gut bacteria is essential to a healthy immune system. “The gut microbiota that resides in the gastrointestinal tract provides essential health benefits to its host, particularly by regulating immune homeostasis. Moreover, it has recently become obvious that alterations of these gut microbial communities can cause immune dysregulation, leading to autoimmune disorders.” [1]

Gut Bacteria Metabolic Activity and Vitamins
* Thiamine, folate, biotin, riboflavin, panthothenic acid are also synthesized by gut bacteria
* It has been estimated that up to half of the daily Vitamin K requirement is provided by gut bacteria
* B vitamins are synthesized by plants, yeasts, and bacteria… and their metabolized by intestinal bacteria

We also know: NAD+ controls the metabolism of Vitamin C and D.
* Autoimmune diseases tend to share a predisposition for vitamin D deficiency, which alters the microbiome and integrity of the gut epithelial barrier
* Metabolic syndrome can prompt imbalances in the gut microbiome, with impaired gut function contributing to toxins in the bloodstream, resulting in vitamin C depletion, which subsequently impairs the trafficking of vitamin E

Healthy Gut Bacteria and COVID-19
There is a connection between COVID-19 and healthy gut bacteria. A recent study demonstrated the connection between gut and SARS-CoV-2 virus’ however, it couldn’t be determined if the lack of healthy gut bacteria resulted in more severe COVID-19, or COVID-19 inhibited healthy gut bacteria. It is possible that both occur.

“Although COVID-19 is primarily a respiratory illness, there is mounting evidence suggesting that the GI tract is involved in this disease. We investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, and whether perturbations in microbiome composition, if any, resolve with clearance of the SARS-CoV-2 virus.” [2]

NAD+ Plus Immune System Diet

1. The role of gut microbiota in immune homeostasis and autoimmunity (NIH)

2. Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 (British Society of Gastroenterology)

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_border76% of Patients Suffer from COVID-long Haulers

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The Lancet published a peer reviewed study entitled “6-month consequences of COVID-19 in patients discharged from hospital: a cohort study”. The study found 76% of patients reported at least one symptom at 6 months after symptom onset. The proportion was higher in women.

The most common ailments were:
fatigue or muscle weakness
sleep difficulties
anxiety or depression
strain in walking or shortness of breath
diffusion impairment

“I am most worried about the unknown future for these patients’ recovery. At six months after symptoms onset, a considerable proportion of Covid-19 patients had physical and psychological problems,” study co-author Lixue Huang of the China-Japan Friendship Hospital and Capital Medical University said. “We still do not know how long it takes for these patients to recover fully from Covid-19 or whether complete recovery is possible in every case.”

“In another complication, 13% of patients who had normal kidney health when they were in the hospital later had reduced kidney function, the study found. That’s a red flag for people who already have potential risk factors for kidney damage, such as high blood pressure and diabetes,” reported STAT.

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderYou Can Not Fight the Rising Tide

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aA “Built atop spongy marsh and old tidal creeks filled with sawdust”
A report by Yale School of the Environment found cities are going to lose the costly battle to hold back the sea.

“It’s a nightmare,” says Ana Zimmerman, who moved her family to higher ground after her James Island home flooded twice.

“wall-off the historic downtown with an 8-mile-long seawall that would cost nearly $2 billion. ”

“In Miami, the Army Corps is studying a 13-foot-high flood wall … Most of the estimated $8 billion price tag would be covered by federal taxpayers … ”

“In Galveston, Texas, the Corps has proposed placing a massive Dutch-style surge gate … estimated cost has ballooned from $2 billion to $37 billion ”

“In New Jersey, the Corps last year published a preliminary plan … Cost estimates range from several billion dollars up to $15 billion.”

“In New York, the Corps proposed building a huge seawall across Lower Manhattan … somewhere between $62 billion and $119 billion”

“In America, we have yet to come to terms with the fact that climate change tells us there are some places where growth is no longer possible.”

“a big wall of distraction”

“Miamians seem to have this horrible concept of permanence of place, even though Miami has only been around a hundred years ”

” the National Flood Insurance Program, which is $20 billion in debt”

“Americans keep flocking to the coast, and builders keep accommodating them. ”

“We’re continuing with more building on a peninsula that’s sinking”

More articles on Flood Insurance, Rising Sea Levels and Global Warming.

bookmark_borderCOVID and DNA Damage-mediated PARP Activation

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COVID-19 causes DNA damage. “DNA damage-mediated PARP activation is the cause of NAD+ depletion. The PARP1 inhibitor ABT-888 prevents the increase in PAR levels, NAD+ depletion and CaT loss. These findings confirm that DNA damage-mediated PARP activation is the cause of NAD+ depletion.

PARP1-mediated synthesis of ADP-ribose chains in turn depletes nicotinamide adenine dinucleotide (NAD+), induces further DNA damage and contractile dysfunction. Accordingly, NAD+ replenishment or PARP1 depletion precludes functional loss. Moreover, inhibition of PARP1 protects against tachypacing-induced NAD+ depletion, oxidative stress, DNA damage. [1]

COVID-long Haulers Syndrome is COVID-19 Induced Secondary Pellagra (CISP). NAD+ depletion causes the body to take drastic action to create more NAD+ including depleting niacin and tryptophan. Exercise or exertion results in PARP activation causing low NAD+. The exertion will cause cardiac problems from the nutritional deficiency and low serotonin from the use of tryptophan will cause problems with your metabolic regulation. Night sweats, intestinal upset, anxiety, and other symptoms are common.

COVID-19: NAD+ Protocol
NAD+ is a crucial part of the immune system. COVID depletes your NAD+. The body needs the time and materials necessary to replenish NAD+. Included in the elements you need are Niacin B3, Vitamin D, Vitamin C, Quercetin, Zinc, and Selenium.

1) DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation

COVID-19 / SARS-CoV-2 / Novel Coronavirus Information

bookmark_borderAir Pollution: the Baby Killer

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Air pollution, both inside and outside the home, contributed to the deaths of about 500,000 newborns in 2019, as reported in the State of Global Air 2020. State Of Global Air 2020 PDF

“The number is just staggering,” reports the epidemiologist that led the stufy, Rakesh Ghosh of the University of California, San Francisco. The study suggests air pollution contributes to about 20% of infant deaths.

“I think you can easily dismiss this finding as something that only happens to people who live far away in thatched roof houses and not to us,” says Niermeyer, a professor at the University of Colorado Medicine. “But air pollution effects our babies, as well.”

bookmark_borderSea Level Rise and Real Estate

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In the research paper, Sea level rise and coastal flooding threaten affordable housing, the authors explain how vast sections of real estate will become uninhabitable in the near future.

Sea Level Rise Impact on Housing
Sea Level Rise Impact on Housing

About Flood Insurance

Do I Need Flood Insurance?
Flood Risks Across the USA Seriously Underestimated
Climate Change: Suspension Of Belief
Climate Denial and Climate Change Change
Underwater: Sea Level Rise
Disaster on the Horizon: The Price Effect of Sea Level Rise
Climate Change And Credit
Real Estate and the Rising Sea Level