bookmark_borderCOVID-19 Testimonial Update — 1 Year Later

January 19, 2021
Today is my one year anniversary of catching COVID-19.
* 24 hours later I started feeling weird — upset stomach and vertigo. Difficulty in falling to sleep with the “spins”.

* Woke up the next morning feeling like I had a severe hangover — headache, body ache, fatigue.

* 72 hours later I could not get out of bed and went 3 or 4 days without a memory.

* For the next 2 weeks I had severe symptoms including nightmares, night sweats, loss of smell and taste, difficulty breathing, cough, fatigue, muscle aches, and then finally diarrhea.

* On February 9, COVID took my father’s life.

* Over the next several months I noticed a recurring pattern of symptoms that would come in waves.

* On May 15, I was diagnosed with COVID Long Haulers Syndrome. My doctor informed me there was no known treatment.

* August of 2020, I met Dr. Ade Wentzel and debated the cause of long haulers — autoimmune response due to inactive particles of the virus Vs. COVID-19 Induced Secondary Pellagra (CISP). I started the Vitamin stack but was taking the wrong type of B3.

* October 15, 2020 I start taking the right type of B3 — nicotinic acid. Immediately, I was relieved of my severe symptoms.

* January 19, 2021:
I’m doing well. I keep pushing myself too hard and some mild symptoms return. Also, I tried reducing the nicotinic acid to 35mg a day and severe symptoms returned. So, I’m sticking to 400mg/day and trying not to push too hard. I am thinking there must be some serious long term cell damage?

The main mild symptom is GI related. Kind of hard to explain… sort-of a feeling of lack of control… like I might piss or poop my pants (but I don’t). I still get muscle soreness that seems more sore than I should from mild exertion. Of particular concern is my lower back and my kidneys.

I also seem to get partial night sweats. Unlike when I had COVID and got it all over my body, now it just happens to my head or parts of my body (last night it was behind my knees.) It’s weird… similar weirdness with my preexisting peripheral neuropathy. I’ve seen much improvement on the stack with virtually no pain nor pins-and-needles. But, sometimes pins-and-needles show up in parts of some fingers (not the entire hands and feet like before.) So, it seems the NAD+ regulation is not uniform over my entire body.

Overall I’m actually better than I was before getting COVID. However, when I tried reducing the nicotinic acid, I got diarrhea and headaches and fatigue (much more like when I was severe long hauling.) So, I guess I’m being treated but not cured. Now, I wonder if I will ever be cured?

Ade says, “You will be cured.” …and, is helping me tweak the Vitamin Stack.

Original COVID Testimonial

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderDroughts and Rising Sea Levels

“There has been a 500% increase in the US drought area,” said Al Roker of the Today show while reporting on 2020 being tied for the hottest year.

The Washington Post reports, “Drought is the sleeper weather story you’ll hear more about in 2021.” [1}

“The impact of desertification is intensifying due to climate change, which is reducing the availability of freshwater, fertile soil, and forest and vegetation. As the degraded land loses value, investments in agriculture and rural development decline even more.” — Ban Ki-moonUnited Nations Secretary-General [2}

This doesn’t have to do with drought episodes. It has to do with areas prone to having droughts. As the area of land that is prone to flooding is increasing exponentially, so too is the land prone to severe, long term drought. We make it even worse by pumping ground water out for agriculture. This depletes the aquifers. The result is sinking land and rising sea levels. The depleted fresh water is then intruded by salt water. Salt water intrusion has a severe impact on the world food supply.

So, you have rising seas above and below the land. Compounding the problem — water expands when it gets warmer. About 1/3 of the rise in sea level is due to thermal expansion of water. [Volumetric Thermal Expansion] The warmer sea water also melts sea ice. The ocean doesn’t reflect the energy the way ice does. In fact just he opposite, the ocean absorbs the heat… making the water warmer… melting more sea ice…. and warming the planet. Which melts the land ice, which raises the sea level. A vicious feedback cycle of fresh water depletion and sea level rise has been created.

Climate change is making weather events more extreme and more frequent. More severe droughts, more severe floods, etc. Energy is being added to the system. “Climate change increases the odds of worsening drought in many parts of the United States and the world in the decades ahead. A changing climate can also alter atmospheric rivers (narrow streams of moisture transported in the atmosphere), which can especially disrupt precipitation patterns in the Western United States. Droughts can persist through a “positive feedback,” where very dry soils and diminished plant cover can further suppress rainfall in an already dry area.” [3]

“Risks from desertification are projected to increase due to climate change (high confidence). The combination of pressures coming from climate variability, anthropogenic climate change and desertification will contribute to poverty, food insecurity, and increased disease burden (high confidence).” [4]

1. Drought is the sleeper weather story you’ll hear more about in 2021. (The Washington Post)
2. DESERTIFICaTION (United Nations)
3. Drought and Climate Change (Center for Energy and Climate Solutions)
4. SPECIAL REPORT: Climate Change and Land Desertification (International Panel on Climate Change)

bookmark_borderGood Gut Bacteria

Your good gut bacteria is essential to a healthy immune system. “The gut microbiota that resides in the gastrointestinal tract provides essential health benefits to its host, particularly by regulating immune homeostasis. Moreover, it has recently become obvious that alterations of these gut microbial communities can cause immune dysregulation, leading to autoimmune disorders.” [1]

Gut Bacteria Metabolic Activity and Vitamins
* Thiamine, folate, biotin, riboflavin, panthothenic acid are also synthesized by gut bacteria
* It has been estimated that up to half of the daily Vitamin K requirement is provided by gut bacteria
* B vitamins are synthesized by plants, yeasts, and bacteria… and their metabolized by intestinal bacteria

We also know: NAD+ controls the metabolism of Vitamin C and D.
* Autoimmune diseases tend to share a predisposition for vitamin D deficiency, which alters the microbiome and integrity of the gut epithelial barrier
* Metabolic syndrome can prompt imbalances in the gut microbiome, with impaired gut function contributing to toxins in the bloodstream, resulting in vitamin C depletion, which subsequently impairs the trafficking of vitamin E

Healthy Gut Bacteria and COVID-19
There is a connection between COVID-19 and healthy gut bacteria. A recent study demonstrated the connection between gut and SARS-CoV-2 virus’ however, it couldn’t be determined if the lack of healthy gut bacteria resulted in more severe COVID-19, or COVID-19 inhibited healthy gut bacteria. It is possible that both occur.

“Although COVID-19 is primarily a respiratory illness, there is mounting evidence suggesting that the GI tract is involved in this disease. We investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, and whether perturbations in microbiome composition, if any, resolve with clearance of the SARS-CoV-2 virus.” [2]

NAD+ Plus Immune System Diet

1. The role of gut microbiota in immune homeostasis and autoimmunity (NIH)

2. Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 (British Society of Gastroenterology)

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_border76% of Patients Suffer from COVID-long Haulers

The Lancet published a peer reviewed study entitled “6-month consequences of COVID-19 in patients discharged from hospital: a cohort study”. The study found 76% of patients reported at least one symptom at 6 months after symptom onset. The proportion was higher in women.

The most common ailments were:
fatigue or muscle weakness
sleep difficulties
anxiety or depression
strain in walking or shortness of breath
diffusion impairment

“I am most worried about the unknown future for these patients’ recovery. At six months after symptoms onset, a considerable proportion of Covid-19 patients had physical and psychological problems,” study co-author Lixue Huang of the China-Japan Friendship Hospital and Capital Medical University said. “We still do not know how long it takes for these patients to recover fully from Covid-19 or whether complete recovery is possible in every case.”

“In another complication, 13% of patients who had normal kidney health when they were in the hospital later had reduced kidney function, the study found. That’s a red flag for people who already have potential risk factors for kidney damage, such as high blood pressure and diabetes,” reported STAT.

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderCOVID and DNA Damage-mediated PARP Activation

COVID-19 causes DNA damage. “DNA damage-mediated PARP activation is the cause of NAD+ depletion. The PARP1 inhibitor ABT-888 prevents the increase in PAR levels, NAD+ depletion and CaT loss. These findings confirm that DNA damage-mediated PARP activation is the cause of NAD+ depletion.

PARP1-mediated synthesis of ADP-ribose chains in turn depletes nicotinamide adenine dinucleotide (NAD+), induces further DNA damage and contractile dysfunction. Accordingly, NAD+ replenishment or PARP1 depletion precludes functional loss. Moreover, inhibition of PARP1 protects against tachypacing-induced NAD+ depletion, oxidative stress, DNA damage. [1]

COVID-long Haulers Syndrome is COVID-19 Induced Secondary Pellagra (CISP). NAD+ depletion causes the body to take drastic action to create more NAD+ including depleting niacin and tryptophan. Exercise or exertion results in PARP activation causing low NAD+. The exertion will cause cardiac problems from the nutritional deficiency and low serotonin from the use of tryptophan will cause problems with your metabolic regulation. Night sweats, intestinal upset, anxiety, and other symptoms are common.

COVID-19: NAD+ Protocol
NAD+ is a crucial part of the immune system. COVID depletes your NAD+. The body needs the time and materials necessary to replenish NAD+. Included in the elements you need are Niacin B3, Vitamin D, Vitamin C, Quercetin, Zinc, and Selenium.

1) DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation

COVID-19 / SARS-CoV-2 / Novel Coronavirus Information

bookmark_borderAir Pollution: the Baby Killer

Air pollution, both inside and outside the home, contributed to the deaths of about 500,000 newborns in 2019, as reported in the State of Global Air 2020. State Of Global Air 2020 PDF

“The number is just staggering,” reports the epidemiologist that led the stufy, Rakesh Ghosh of the University of California, San Francisco. The study suggests air pollution contributes to about 20% of infant deaths.

“I think you can easily dismiss this finding as something that only happens to people who live far away in thatched roof houses and not to us,” says Niermeyer, a professor at the University of Colorado Medicine. “But air pollution effects our babies, as well.”

bookmark_borderNAD+ Plus Immune System Diet (CISP CPD)

By Daniel Brouse
help@membrane.com

THE NAD+ PLUS DIET (COVID Induced Secondary Pellagra and COVID Prevention Diet)

The NAD+ Plus Diet is based on research by Dr. Ade Wentzel (Port Elizabeth, South Africa), Robert Miller (Cape Town) and Guy Richards (Johannesburg). The team of scientist developed a diet based protocol that boosts NAD+ and the immune system.

THE PROTOCOL: Niacin B3, Vitamin D, Vitamin C, Quercetin, Zinc, and Selenium

Boosting NAD+ is of particular importance when it comes to COVID-19. NAD+ (nicotinamide adenine dinucleotide) is in every cell of your body. NAD+ is involved in cell creation, maintenance, metabolism, and regulating cell processes. COVID both increases the breakdown of NAD+ and decreases the production of NAD+. If you have suboptimal NAD+ prior to contracting COVID, the coronavirus is likely to make the symptoms more severe and persist longer in duration (resulting in death.) Boosting your NAD+ can also help with aging, hypertension, type 2 diabetes, and most other ailments and illness.

By maintaining lifestyle and diet, COVID-19 can be prevented and/or shortened in severity and duration. COVID-long Haulers Syndrome can be cured. Long haulers syndrome is COVID-19 Induced Secondary Pellagra (CISP).

THE DIET TO BOOST THE IMMUNE SYSTEM WITH NAD+
Quercetin
Coffee and red wine are rich in Quercetin. Dieting can be fun. Quercetin is a bioflavonoid found in fruits and vegetables. There isn’t a Recommended Daily Allowance and the dosage depends on your weight; however, at least a 100mg per day is a good rule of thumb. 500-1000mg per day may be needed to boost NAD+. The highest levels are found in:

  • Onions 19.36mg per 100g serving [Red onion 32mg]
  • Dill (fresh) 55mg per 100g serving
  • Hot wax yellow peppers, raw 50mg per 100g serving
  • Radish leaves 70mg per 100g serving
  • Cilantro 53mg per 100g serving
  • Capers 173mg per 100g serving

Zinc
The Recommended Daily Allowance of Zinc is 10-15mg per day.

  • Water. Drinking water is rich in Zinc. Do not drink filtered water. Do not drink purified bottled water. Zinc is naturally present in water. The amount of Zinc in your water depends on the local geology and hydrologic cycle. The World Health Organization says, “In natural surface waters, the concentration of zinc is usually below 10 µg/litre, and in groundwaters, 10–40 µg/litre. In tapwater, the zinc concentration can be much higher as a result of the leaching of zinc from piping and fittings.” WARNING: If you live in an area where it is not safe to drink the water, or the zinc in the water is not sufficient, you may need to take a 10-15mg supplement.
    Nutrients In Drinking Water
    USDA Study shows regional mineral content of public and well water.
  • Meat and marine organisms contain 10–50 mg/kg wet weight

Vitamin C
The Recommended Daily Allowance of Vitamin C is 60mg per day. For NAD+ boosting, 500-1000mg may be required. Whole foods are recommended. Juicing may provide higher concentrations of Vitamin C; however, other nutritional benefits are lost in the process. You may need to supplement your diet with 500mg of Vitamin C per day.

  • Red pepper, sweet raw 95mg per 1/2 cup serving
  • Orange 70mg per serving
  • Broccoli cooked 39mg per 1/2 cup serving
  • Strawberries 49mg per 1/2 cup serving
  • Potato 17mg per 1/2 cup serving
  • Tomato 17mg mg per 1/2 cup serving

Vitamin D
The Recommended Daily Allowance of Vitamin D is 600-1,000iu per day. For NAD+ boosting, you may need to supplement your diet with 1,000-2,000iu of D3 per day. Few foods naturally contain vitamin D.

  • Sunlight. 15 minutes of sunshine per day. 90% of your body’s Vitamin D comes from the photosynthesis of sunlight to the skin. UVB light causes a reaction resulting in Vitamin D and other photoproducts essential for a healthy immune system. WARNING: UVB can cause cancer.
  • Fatty fish and seafood / Trout 645iu per serving
  • Mushrooms 366iu per 1/2 cup raw
  • Egg yolks 44iu per 1 scrambled egg
  • Fortified milk 120iu per cup

Selenium
The Recommended Daily Allowance of Selenium is 55mcg per day. Care should be taken not to overdose on Selenium. Consuming 50 Brazil nuts in one day can lead to selenosis resulting in breathing problems, heart attack, kidney failure, and death. Selenium supplements are not recommended.

  • Brazil nut 1 (one) 78mcg
  • Shrimp 3oz 40mcg
  • Chicken 3oz white meat 22mcg
  • Beef 3oz 18mcg

Niacin B3
The Recommended Daily Allowance of Niacin is 16mg per day. Niacin is your main precursor to creating NAD+. It is the most important component of the diet. It is also the most difficult to find sufficient quantities of in food. Most Americans get their Niacin from fortified breakfast cereal. Niacin is sprayed on the outside along with several other vitamins. It would take 100 bowls of Wheaties/day to correct a niacin deficiency. To obtain the amount of Niacin needed from a natural diet would require 4 pounds of liver a day or 62 pounds of cabbage (not recommended). You will likely need to supplement your diet with 50-100mg of Niacin per meal in order to boost your NAD+ and immune system. Nicotinic acid is essential, NOT nicotinamide.

  • Beef liver pan fried 3oz 15mg
  • Chicken breast 3oz 10mg
  • Marinara (spaghetti) sauce, ready to serve, 1 cup

Conclusion
Having survived COVID-19, I became inflicted with COVID-long Haulers Syndrome. After searching for a cause and a cure, I found The Vitamin and Mineral Protocol. The dosage depends on your age, weight, preexisting conditions, and what COVID has done to your body. The above diet is what cured me. You may need to increase the dosage of supplements.

COVID-19 Testimonial
Getting and Recovering from COVID.

The NAD+ Plus Immune Boosting Diet may treat other conditions. If you are on drugs to help regulate your preexisting conditions, you may need to reduce your dosage. Perhaps someone on Lisinopril for high blood pressure, or Warfarin to thin their blood, or maybe Metformin for their type 2 diabetes, should have concern that replenishing your NAD+ will cause the medication to be too strong. You should check with your doctor about lowering your dosage.

Robert Miller said, “Metaformin is a complex 1 inhibitor that will mess with NAD+ redox and NAD+ levels. As for lowering doses, yes, NAD+ boosting is highly likely to create a need to lower some medication but this must be done with a medical professional.”

Ade Wentzel added, “Quercetin and Warfarin should be monitored as the Warfarin effect may be changed. Nicotinic acid can reduce blood pressure and blood sugar in those with raised numbers so this needs to be monitored carefully.”

ADDITIONAL RESOURCES
COVID-19 / SARS-CoV-2 / Novel Coronavirus

COVID-19 Emergency Management Plan

COVID: The Cure?
Could Nicotinamide adenine dinucleotide (NAD+) be both a prophylactic and a treatment for COVID-19?

COVID-19: NAD+ Protocol
NAD+ is a crucial part of the immune system. COVID depletes your NAD+.
Included in the elements you need are Vitamin B3, Vitamin D, Vitamin C, Quercetin, Zinc, and Selenium.

COVID Long Haulers Syndrome: NAD+ Deficiency
Research by Ade Wentzel, Robert Miller, and Guy Richards has found COVID-long (Long Haulers Syndrome) is a result of an NAD+ deficiency caused by SARS-CoV-2 (novel coronavirus).

bookmark_borderVitamin and Mineral Supplements

In general, you should get your vitamins and minerals in the food you eat and water you drink as part of your natural diet.

It is difficult to find a multivitamin that is good for you. Taking metals, such as, Iron, Sodium, Magnesium, Potassium, or Calcium as a supplement can be dangerous. Usually Zinc is on the list; however, very controlled amounts of Zinc are recommended for NAD+ deficiencies. Metals are not good in supplements unless advised by a doctor to treat a specific condition. Besides being toxic in supplement form, supplements bypass the important parts of nutrition and the digestive process. For instance, “Fiber is incredibly important. It leaves your stomach undigested and ends up in your colon, where it feeds friendly gut bacteria, leading to various health benefits. Certain types of fiber may also promote weight loss, lower blood sugar levels, and fight constipation.”

You should get all your minerals from the food and water you intake. When you get your minerals from the food you eat, they are part of the metabolic process. The same holds true for hormones and amino acids. Don’t take the supplement. Let your body create them — melatonin, tryptophan, serotonin, Vitamin D. “Essential minerals are most potent when they come from food. But if you’re struggling with deficiencies, you may need to take supplements. If so, use caution: ingesting too much of a mineral supplement can be harmful.” — Harvard Health “Precious metals and other important minerals for health”

The exception to this rule is if you want to prevent COVID or recover from COVID-19. A safe and effective prophylactic to prevent COVID, a treatment for active COVID cases, and a protocol for post-COVID long haulers syndrome is available. The primary ingredient is Niacin B3.

THE PROTOCOL
Niacin B3, Vitamin D, Vitamin C, Quercetin, Zinc, and Selenium.

The following doses have cured severe deficiencies in COVID-long cases:
* Vitamin C, Quercetin and Selenium you can get from your diet. Careful not too much Selenium. One (1) Brazil nut a day is adequate Selenium.
* The Vitamin D is best gotten from 15 minutes a day in the sun. You can take 1000iu/day supplement, too.
* A 15mg Zinc/day supplement. Care should be taken not to overdose on Zinc. There are many zinc products which deliver different amounts of free zinc per milligram.
* The Niacin is the trickiest and most important part. You need to make sure you get the right kind of B3. Non-flush is no good. You can start with 35mg/day, but it will depend on your deficiency. The cured long hauler takes 100mg with each meal. (For a 6 month duration.)

Niacin is the most important ingredient in the protocol. Niacin is used to replenish NAD+. The other ingredients can not be processed without NAD+. Taking mega doses of Vitamin C or Vitamin D are of little to no help without NAD+.

The protocol was developed by Dr. Ade Wentzel (Port Elizabeth, South Africa), Robert Miller (Cape Town) and Guy Richards (Johannesburg). They developed the diet based protocol as a result of their research COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity.

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderAfter You Recover from COVID-19 Induced Secondary Pellagra (CISP) Long Haulers

Research by Ade Wentzel, Robert Miller, and Guy Richards has found COVID-long (Long Haulers Syndrome) is COVID-19 Induced Secondary Pellagra (CISP) and is a result of an NAD+ deficiency caused by COVID-19.

You can boost your NAD+ levels with the Anti-COVID Protocol: Niacin B3, Vitamin D, Vitamin C, Quercetin, Zinc, and Selenium

If you were NAD+ deficient prior to COVID and recovered using the Protocol, you should consult with your doctor about any preexisting conditions you were being treated for. If you were on drugs to help regulate your preexisting conditions, you may need to reduce your dosage. Perhaps someone on Lisinopril for high blood pressure, or Warfarin to thin their blood, or maybe Metformin for their type 2 diabetes, should have concern that replenishing your NAD+ will cause the medication to be too strong. You should check with your doctor about lowering your dosage.

Robert Miller said, “Metaformin is a complex 1 inhibitor that will mess with NAD+ redox and NAD+ levels. As for lowering doses, yes, NAD+ boosting is highly likely to create a need to lower some medication but this must be done with a medical professional.”

Ade Wentzel added, “Quercetin and Warfarin should be monitored as the Warfarin effect may be changed. Nicotinic acid can reduce blood pressure and blood sugar in those with raised numbers so this needs to be monitored carefully.”

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderCOVID-19 Induced Secondary Pellagra (CISP) and the Coronavirus Code

By Daniel Brouse
help@membrane.com

Coronavirus / COVID

Three scientists from South Africa have cracked the COVID code. COVID Long Haulers Syndrome is COVID Induced Secondary Pellagra (CISP).

By treating the population for pellagra:
* many new COVID cases can be prevented (prophylactic)
* the severity and duration of COVID symptoms can be reduced
* COVID-long Haulers Syndrome can be treated

THE PROTOCOL: Niacin B3, Vitamin D, Vitamin C, Quercetin, Zinc, Methyltetrahydrofolate, and Selenium.

The dosage depend on your Niacin B3 deficiency. COVID causes a Niacin deficiency. In addition, many people are deficient prior to contracting COVID. These cases often end in death (aged, hypertension, obese, and type2 diabetics.)

The following doses have treated severe niacin and NAD+ deficiencies in COVID-long cases:
* Vitamin C, Quercetin and Selenium you can get from your diet. Careful not too much Selenium. One (1) Brazil nut a day is adequate Selenium.
* The Vitamin D is best gotten from 15 minutes a day in the sun. You can take 1000iu/day supplement, too.
* A 15mg Zinc/day supplement. Care should be taken not to overdose on Zinc. There are many zinc products which deliver different amounts of free zinc per milligram.
* Methyltetrahydrofolate 130-400ug/day
* The Niacin is the trickiest and most important part. You need to make sure you get the right kind of B3. Non-flush is no good. You can start with 35mg/day, but it will depend on your deficiency. The treated long hauler takes 100-150mg with each meal. Supplementation is still necessary for an undetermined amount of time.

Niacin is the most important ingredient in the protocol. Niacin is used to replenish NAD+. The other ingredients can not be processed without NAD+. Taking mega doses of Vitamin C or Vitamin D are of little to no help without NAD+.

The protocol was developed by Dr. Ade Wentzel (Port Elizabeth, South Africa), Robert Miller (Cape Town) and Guy Richards (Johannesburg). They developed the diet based protocol as a result of their research COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity.

This is not the first time the world has seen a pellagra epidemic. “In the early 1900s, pellagra reached epidemic proportions in the American South. Between 1906 and 1940 more than 3 million Americans were affected by pellagra with more than 100,000 deaths, yet the epidemic resolved itself right after dietary niacin fortification.” (Pellagra – Wikipedia)

In 2000, the World Health Organization developed an emergency management plan for pellagra.

WHO Pellagra Prevention and Control (PDF)

MORE ON COVID: COVID-19 / SARS-CoV-2 / Novel Coronavirus