bookmark_borderCOVID-19 and Air Pollution

COVID-19
by Daniel Brouse
March 25, 2020
Email: help@membrane.com

Abstract: Many compromised respiratory and immune systems are a result of air pollution. COVID-19 is having a larger impact on the population due to underlying compromised respiratory and immune systems caused by air pollution.

Hypothesis:
Large portions of the world are susceptible to particulate and ozone pollution. In this study, the focus is on particulate pollution. Though tropospheric ozone pollution is thought to be more detrimental to the respiratory and immune systems, current technology makes it too difficult to measure. Tropospheric ozone and particulate pollution are common in urban and industrial areas. Ozone is created when the ultraviolet light, temperature, and chemicals in the air create a chemical reaction. The result is millions of micro-explosions in the lungs. Hot summer days are optimal for ozone creation. Particulate pollution is a result of fine particles suspended in the atmosphere. Particulate pollution is easier to be aware of because you can see it as haze or smog in the air. Exposure to ozone and particulate pollution results in permanent lung damage and chronic immune system disorders. Exercising in the out-of-doors during days with high pollution amplifies the damage to the respiratory and immune systems. The larger the pollution intake, the more severe the damage.

Exposure to air pollution and COVID-19 mortality
The Harvard study Fine particulate matter and COVID-19 mortality in the United States found, “A small increase in long-term exposure to PM2.5 leads to a large increase in COVID-19 death rate, with the magnitude of increase 20 times that observed for PM2.5 and all-cause mortality. The study results underscore the importance of continuing to enforce existing air pollution regulations to protect human health both during and after the COVID-19 crisis. The data and code are publicly available.” [1]

A study from Oxford found, “Our results suggest that air pollution is an important cofactor increasing the risk of mortality from COVID-19. This provides extra motivation for combining ambitious policies to reduce air pollution with measures to control the transmission of COVID-19.” [2]

“The study estimated that about 15% of deaths worldwide from COVID-19 could be attributed to long-term exposure to air pollution. In Europe the proportion was about 19%, in North America it was 17%, and in East Asia about 27%,” reports the European Society of Cardiology. [3]

Pollen and Increased Risk of Infection
The Proceedings of the National Academy of Sciences of the United States of America published the study Higher airborne pollen concentrations correlated with increased SARS-CoV-2 infection rates, as evidenced from 31 countries across the globe.

The research showed that airborne pollen on average accounts for 44% of the variation in infection rates in addition to humidity and air temperature. Pollen exposure weakens the immunity by diminishing the antiviral interferon response.

Update: August 2021
Excess of COVID-19 cases and deaths due to fine particulate matter exposure during the 2020 wildfires in the United States

“The presence of wildfire smoke last year during the pandemic may have been responsible for at least 19,000 additional cases of COVID-19 on the West Coast, and 700 subsequent deaths.”

“The year 2020 brought unimaginable challenges in public health, with the confluence of the COVID-19 pandemic and wildfires across the western United States. Wildfires produce high levels of fine particulate matter (PM2.5). Recent studies reported that short-term exposure to PM2.5 is associated with increased risk of COVID-19 cases and deaths. We acquired and linked publicly available daily data on PM2.5, the number of COVID-19 cases and deaths, and other confounders for 92 western U.S. counties that were affected by the 2020 wildfires. We estimated the association between short-term exposure to PM2.5 during the wildfires and the epidemiological dynamics of COVID-19 cases and deaths. We adjusted for several time-varying confounding factors (e.g., weather, seasonality, long-term trends, mobility, and population size). We found strong evidence that wildfires amplified the effect of short-term exposure to PM2.5 on COVID-19 cases and deaths, although with substantial heterogeneity across counties.”

Negative Feedback Loops
Long term exposure to air pollution causes COVID co-morbidities including respiratory disease, cardiovascular disease, and a compromised immune system. Contracting COVID exacerbates the preexisting co-morbidities. Post-COVID exposure to air pollution further compromises the co-morbidities. The negative feedback loop repeats until failure.

Increased Risks Due to Reinfection
The study Acute and postacute sequelae associated with SARS-CoV-2 reinfection was published in the Journal Nature.

* The evidence shows that reinfection further increases risks of death, hospitalization and damage to multiple organ systems
* COVID exacerbates underlying conditions including pulmonary, cardiovascular, hematological, diabetes, gastrointestinal, kidney, mental health, musculoskeletal and neurological disorders

First infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with increased risk of acute and postacute death and sequelae in various organ systems. Compared to no reinfection, reinfection contributed additional risks of death, hospitalization, and sequelae including pulmonary, cardiovascular, hematological, diabetes, gastrointestinal, kidney, mental health, musculoskeletal and neurological disorders. The risks were evident regardless of vaccination status. The risks were most pronounced in the acute phase but persisted in the postacute phase at 6 months. Compared to noninfected controls, cumulative risks and burdens of repeat infection increased according to the number of infections. Limitations included a cohort of mostly white males. The evidence shows that reinfection further increases risks of death, hospitalization and sequelae in multiple organ systems in the acute and postacute phase. Reducing overall burden of death and disease due to SARS-CoV-2 will require strategies for reinfection prevention.

Minimize Your Risk
1) Minimize your exposure to air pollution by checking the air quality conditions in your location. (Get air quality data where you live.)
2) People at high risk of COVID mortality due to co-morbidities, such as, aged, obese and type2 diabetics, combined with long term exposure to air pollution should take preventative measures. A deficiency of nicotinamide adenine dinucleotide (NAD+) may be the primary factor related to the SARS-Cov-2 disease spectrum and the risk for mortality, as subclinical nutritional deficiencies may be unmasked by any significant increase in oxidative stress. [4]

The Miller/Wentzel/Richards prophylactic protocol of Niacin B3, Vitamin D, Vitamin C, Quercetin, Zinc, and Selenium can minimize the severity and duration of COVID symptoms and may prevent death.

1. Fine particulate matter and COVID-19 mortality in the United States Harford
2. Regional and global contributions of air pollution to risk of death from COVID-19 Oxford
3. Study estimates exposure to air pollution increases COVID-19 deaths by 15% worldwide European Society of Cardiology
4. COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity Miller, Wentzel, Richards

Additional References:
Pollen and Increased SARS-CoV-2 Infection Rates
https://projects.iq.harvard.edu/…/pm_and_covid_mortality.pdf
https://projects.iq.harvard.edu/files/covid-pm/files/pm_and_covid_mortality_supp.pdf
https://www.medrxiv.org/content/10.1101/2020.04.05.20054502v1

CLIMATE RELATED UPDATES

Climate-Driven Health Collapse: The Compounding Feedback Loops of Disease, Pollution, and Extreme Weather Brouse (2025)

COVID-19 Index

bookmark_borderAir Quality and Climate Change

Current models indicate an increase in air quality alerts. The increase risk is not necessarily from an increase in pollution. An on-going research study conducted by InternetU.org suggests a warming climate is likely contributing to reduction in air quality.

The frequency of air quality alerts is on the rise in the United States and many other parts of the world. The Philadelphia Area is a prime example. Philly and suburbs have had multiple days in a row when it was unhealthy to breath. The Action Alert days are also starting earlier in the season and lasting longer into the summer. In fact, a recent string of days with temperatures above 90 have resulted in an Action Alert on September 25, 2017.

Ozone Action Alert for September 25, 2017
Ozone Action Alert for September 25, 2017

When the Earth’s surface temperature is hot enough and sunlight provides enough ultraviolet light, Nitrogen Oxides (NOx) and Volatile Organic Compounds (VOCs) in the air create a chemical reaction. The result is ozone. Tropospheric ozone is very destructive to plants and animals. Tropospheric ozone is killing an unprecedented number of trees. Unfortunately, it is also causing a massive amount of respiratory and immune system problems in humans, such as, asthma.

Check the current Air Quality Index

More About Ozone

bookmark_borderWhy “Fresh Air and Sunshine” is Dangerous

By Daniel Brouse

Q: Do you know what are two of the most dangerous exposures for children and the elderly?
A: Fresh air and sunshine. Either may be hazardous; however, when fresh air and sunshine are combined, the result can be extreme.

On days like today, do not go out and play.

The sun can damage your skin and cause cancer. Air pollution causes many health risks, too.


Fresh Air + Sunshine = Dangerous

Sunshine is also part of a deadly reaction. When combined with heat and volatile gases in the air, ultraviolet light causes a deadly reaction. The result is tropospheric ozone.

The dangerous ozone (O3) is created when vehicle (and other) exhaust is not completely combusted. Nitrogen Oxides (NOx) and Volatile Organic Compounds (VOCs) in the exhaust react to temperature and sunlight creating tropospheric ozone (O3).

The ozone in the air can cause permanent damage to your respiratory and immune systems. Millions of micro-explosions enter through your mouth and nose (and to some extent eyes, ears and skin)… then, if lucky, complete their short lives in your lungs. (NOTE: Lucky, for the length of their life. Unlucky, for the length of yours.)

bookmark_borderWARNING! Hold Your Breath / Air Quality Alert

By Daniel Brouse

Many days in the Philadelphia region are not healthy for breathing. On “Ozone Action Alert Days” you are advised to avoid outside activities. Children should not play outdoors. Avoid running and other fitness activities. Do not breathe in unconditioned air. Low level ozone is volatile and causes micro-explosions in your lungs that result in chronic respiratory and immune system damage. The more and harder you breathe, the more damage you cause to your body. Avoid exercise.

Pollution is the leading cause of death and illness. Low level (tropospheric) ozone is a major contributor to air pollution diseases.

Also see: “Why Fresh Air + Sunshine = Dangerous”

View the current air quality for Philadelphia.

The Philadelphia Region started the season with three Action Alert days in a row.

June 13, 2017

Dangerous Air Quality / June 13, 2017
Dangerous Air Quality / June 13, 2017

June 12, 2017

Unhealthy Air Quality June 12, 2017
Unhealthy Air Quality June 12, 2017

June 11, 2017

Unhealthy Air Quality June 11, 2017
Unhealthy Air Quality June 11, 2017

NOTE: Graphics are from the EPA (Environmental Protection Agency of the United States of America)

Death By Ozone | The Ozone Know Zone

Ozone is not only killing humans, it is also killing the trees. The chain reaction is known as an adverse feedback loop.

Dying Trees, The Membrane Domain

  1. Tree Death Questions
  2. The Earth’s Status
  3. Answers About Ozone and Dying Trees
  4. Ozone Questions Part 4
  5. Ozone Answers Part 5

bookmark_borderBackground Ozone

Low level ozone (Tropospheric Ozone) is deadly to plants and animals. The huge increase in human respiratory problems and asthma is largely attributed to ozone.

NASA has released a new study on ozone pollution:

Levels of “background ozone” — ozone pollution present in a region but not originating from local, human-produced sources — are high enough in Northern California and Nevada that they leave little room for local ozone production under proposed stricter U.S. ground-level ozone standards, finds a new NASA-led study.

The researchers, led by Min Huang of George Mason University, Fairfax, Virginia, used a novel technique that combined data acquired from two instruments on NASA’s Aura spacecraft in the summer of 2008. The technique more accurately determines levels of background ozone and their relative contribution to total surface ozone levels. Integrating Aura satellite data into the study increased the estimates of background ozone by an average of 2.4 parts per billion (ppb) over previous estimates, an amount that varied by 4 to 11 ppb over the two states. Huang conducted the study while a postdoctoral scholar at NASA’s Jet Propulsion Laboratory, Pasadena, California.

The new method of integrating satellite data may help provide states with a scientific basis to request exemptions to the federal air quality standards for ground-level ozone proposed by the U.S. Environmental Protection Agency. EPA proposed lowering the standard from the current 75 ppb set in 2008 to between 65 and 70 ppb, following a review of public data on the negative health effects of ozone pollution. EPA is required to announce a final decision by Oct. 1.

Background ozone can be produced from natural local sources such as wildfires, and transported via winds from distant sources, such as the stratosphere or another region or country.

Monthly-mean maximum daily 8-hour average background ozone concentration in parts per billion in California and Nevada
Monthly-mean maximum daily 8-hour average background ozone concentration in parts per billion in California and Nevada, estimated by integrating data from NASA’s Aura spacecraft. Credit: NASA/JPL-Caltech/George Mason University

The NASA study found that, on average, background ozone sources generated about 48.3 ppb, or 77 percent, of the total ozone in the study region of California and Nevada. The findings are particularly important in Northern California and Nevada, where wildfires and ozone transported to the region from abroad can cause background ozone to exceed 60 ppb. The lowest background ozone levels were seen in Southern California, where topography helps trap local emissions.

“Our study shows background ozone plays a significant role in Western U.S. ozone levels under high-ozone conditions, and varies considerably by region, with higher values in many rural regions,” said Kevin Bowman, study co-author and principal investigator of Aura’s Tropospheric Emission Spectrometer (TES) instrument at JPL. “Some regions in the West have high background ozone levels that leave less than 10 parts per billion for local ozone production under the EPA’s most aggressive proposed ground-level ozone standards.”

To more accurately determine which sources are contributing the ozone, the team developed a multi-scale pollution assimilation system that ingests global ozone data from Aura’s TES instrument with nitrogen dioxide data from Aura’s Ozone Monitoring Instrument (OMI). Data from independent aircraft, ozonesondes (balloon-borne instruments that measure the concentration of ozone at various altitudes) and surface monitoring sites tested the system’s predictions. The team estimated the contribution of local and background ozone at surface monitoring sites when ozone levels exceeded EPA thresholds.

Ninety percent of ozone is found in Earth’s stratosphere, where it protects us from harmful ultraviolet radiation. The rest is found in Earth’s lower atmosphere, the troposphere, where it acts as a greenhouse gas. At ground level, however, ozone is a key component of smog, produced when nitrogen oxides photochemically react with sunlight in the presence of volatile organic compounds. Ground-level ozone also affects human and ecosystem health. Nitrogen dioxide, the most important ingredient in the production of ozone, comes primarily from cars and industrial emissions, as well as natural sources, such as wildfires.

Critics of EPA’s proposed new standard argue it would throw many areas out of compliance, resulting in economic burdens, and that much of the ozone in their regions comes from non-local pollution. When a county or area is found to be out of compliance, it must act to reduce its ozone emissions. Proponents of the new standard argue the reductions are essential to protect public health. EPA is not allowed to consider economic costs in its decision.

Contributions of background ozone and local, human-produced emissions to ozone levels greater than 65 parts per billion at surface sites in various regions.
Contributions of background ozone (green bars) and local, human-produced emissions to ozone levels greater than 65 parts per billion (horizontal red dash line) at surface sites in various regions. Credit: NASA/JPL-Caltech/George Mason University

The Clean Air Act allows states to request an exemption to the ozone standard if they can show that the cause of an air-quality violation is due to ozone from outside the country or from natural causes. To date, only Wyoming has been granted an exceptional event clearance by EPA due to high background ozone levels.

“By assimilating NASA satellite data on ozone and nitrogen dioxide, our study improves calculations of total and background ozone levels from both non-local ozone and wildfires, data that may prove useful to policymakers,” said Huang. “Our method can potentially be applied broadly to predict air quality in other time periods and locations. We plan to conduct follow-up studies over longer time periods, especially during higher wildfire periods.”

Bowman points to a recent NASA study that showed pollution entering the western United States from Asia has offset expected reductions in mid-tropospheric ozone from local sources. “The partitioning between background and local human sources will likely change in the future, as emissions from outside the United States continue to increase, and contributions from drought-related wildfires grow due to climate change. These changes will require additional reductions in local human-produced emissions to meet EPA standards.”

Bowman said the results highlight the importance of a new international constellation of low-Earth orbiting and geostationary satellites that will continuously observe pollution over Asia, Europe and North America, including NASA’s planned Tropospheric Emissions: Monitoring of Pollution (TEMPO) mission. “This constellation will be a game changer in quantifying global sources of local pollution,” he said.

Study results were published recently in the Journal of Geophysical Research: Atmospheres. Other participating institutions include the University of Iowa, Iowa City; NOAA, College Park, Maryland; University of Colorado, Boulder; and NASA’s Goddard Space Flight Center, Greenbelt, Maryland. JPL is managed for NASA by the California Institute of Technology in Pasadena.