bookmark_borderOcean Warming and Climate Change

Q: How much of global warming is in the ocean?
A: 90%

Q: How long will it take for the ocean temperature to return to normal?
A: Hundreds of years
“The irreversibility of this ocean warming on centennial timescales creates additional requirements for climate policy, particularly considering the widespread impacts.”

Q: What is my greatest concern?
A: The rate of warming is accelerating… and the warmer the ocean, the less carbon the ocean absorbs… creating a nasty feedback loop.

“Increasing anthropogenic greenhouse gas (GHG) concentrations cause a positive Earth energy imbalance (EEI), with resulting surplus heat in the climate system increasing ocean heat content (OHC). Unprecedented oceanic warming has been observed since at least the 1950s, reaching record values from 2012–2021. This oceanic warming has been pervasive, spreading from the surface to the abyssal layers, and with the long-term OHC trend accelerating.”

These were the finding reported in the Nature Reviews Earth & Environment report Past and Future Ocean Warming

Impacts and consequences of ocean warming

Observed and projected ocean warming has substantial impacts across major Earth system components and scales (Fig. 1). For example, ocean warming accounts for more than 1/3 of global-mean sea level rise through thermal expansion, and thus dominates regional sea level patterns82,202. Sea level rise, in turn, increases the risks for coastal infrastructures and coastal habitats from salt water intrusion, coastal erosion and flooding in low-lying regions232,233 (Fig. 1b). Ocean warming also decreases ocean density and increases upper-ocean stratification by 5.3% since 1960 (ref.234) (Fig. 1b), affecting the vertical and lateral exchanges of heat, carbon, oxygen, nutrients and other substances. The stratification increase, solubility reduction and circulation changes drive deoxygenation in the ocean interior by ~0.5–3.3% since the 1960s (refs.6,235). By changing sea water buoyancy, ocean warming impacts ocean currents, for example, accelerating the zonally averaged Southern Ocean zonal flow in the upper layer174. Warmer water also reduces the efficiency of oceanic carbon uptake and storage28,236 (Fig. 1b). The compounded effect of each of these impacts, especially following extreme events236,237,238, poses more substantial stress on the environment than their individual effects236 (Fig. 1b), driving, for example, changes in net primary and export production239,240 with socioeconomic impacts on marine fisheries and aquaculture systems241,242. Indeed, it is projected that, driven by multiple stressors, the maximum catch potential of tropical fish stocks in some tropical exclusive economic zones will decline by up to 40% by the 2050s under the RCP8.5242.

MHWs offer a strong example, whereby the relentless increase in OHC has direct implications for the frequency, intensity and extent of MHWs and other ‘hot spots’ within the ocean (Fig. 1b). With human-induced global warming and higher ocean heat content, it is inevitable that MHWs become more abundant, extensive and longer-lasting237. The highly anomalous ocean waters, including SSTs and upper OHC, often persist for more than a month243, resulting in large impacts on ocean ecosystems and marine life. Effects from thermal stress causes mass mortality of benthic communities, including coral bleaching, changes in phytoplankton blooms, adverse effects on kelp forests and sea grasses, toxic algal blooms, shifts in species composition and geographical distribution, and decline in fish and fisheries and seabirds105,238. As such, MHWs modify ecosystem assemblages, biodiversity, population extinctions and redistribution of habitat244,245.

One example is the prolonged MHW known as ‘the blob’ in the northeast Pacific and Gulf of Alaska from 2014–2016. This event greatly affected the ocean food web, shrinking phytoplankton blooms, which, in turn, diminished copepods, zooplankton and krill, and small fish, leading to the demise of ~1 million birds (notably murres), ~100 million cod and hundreds of humpback whales104,105. A similar unprecedented MHW in the south Tasman Sea in 2015–2016, where SSTs were up to 2.9 °C above normal owing to an ENSO-related alteration of the ITF and East Australian Current119, also had substantial impacts246. Ecosystem impacts ranged from new disease outbreaks in farmed shellfish (oysters, abalone) and salmon, to mass mortality of wild mollusks, and many out-of-range observations of several fish species. Thus, with continued warming, MHW events and their impacts are expected to worsen: climate models project that the frequency of MHW might increase 50 times by 2081–2100 relative to 1850–1900 under RCP8.5 (ref.247).

Ocean warming also intensifies tropical cyclones248, and associated changing ocean surface currents can indirectly affect pathways of storms139 (Fig. 1b). In August 2017, the Gulf of Mexico became the warmest on record to that point in the summertime. There was a strong link between upper OHC and record high rainfalls of over 60 inches (1,520 mm) over five days and extensive flooding in hurricane Harvey over parts of Texas249. Other processes at the air–sea interface affected by ocean warming include an increase of surface evaporation and rainfall12,13, and an increase in precipitation anomalies tied to ENSO, and associated extreme weather events250,251 (Fig. 1b).

Implications of ocean warming are also widespread across the Earth’s cryosphere195, and have in turn affected the ocean itself 252 (Fig. 1b). Examples include the thinning of floating ice shelves and marine terminating glaciers from basal ice melt21,253, and the retreat and speedup of ice-sheet outlet glaciers in Greenland and Antarctica254 and of tidewater glaciers in South America and in the Arctic255.

Other particular concerns are the potential abrupt changes associated with warming, such as ocean circulation (for example, AMOC)256 and ocean ecosystems6,248. Ocean warming is a key driving element for AMOC changes. The potential for abrupt AMOC collapse as a ‘low-probability, high-impact’ event cannot be ruled out in the future6,247. Each species of marine organisms has an optimal temperature window for functioning; most organisms are therefore vulnerable to warming257. It is projected that most tropical coral reefs will be threatened258.
Summary and future perspectives

In summary, OHC has changed substantially since the 1950s and is projected to continue to do so in the future. In the upper 2,000 m, net global increases of 351.4 ± 59.8  ZJ (0.36 ± 0.06 W m−2) have been observed from 1958 to 2019, with the rate of warming accelerating from ~0.0–0.3 W m−2 in the 1960s to ~0.5–0.7 W m−2 in the 2010s. The pattern of ocean warming has been non-uniform in this historical era, including strong warming in the Atlantic and southern oceans, and overall is dominated by the redistribution of ocean heat by currents. Relative to 2005–2019, future warming is projected to reach 1,030 [839–1,228] ZJ for SSP1-2.6 and 1,874 [1,637–2,109] ZJ for SSP5-8.5 at the end of this century, ~2–4 (SSP1-2.6) to ~4–6 times (SSP5-8.5) the observed 1958–2019 change. On these timescales, added heat has an important role for OHC projections. Moreover, low GHG emissions would be likely to lead to a detectable and lasting reduction in ocean warming rate, with noticeable reductions in climate-change impacts. Indeed, given that ocean warming has already led to pervasive impacts and consequences, monitoring, understanding, adapting to and mitigating ocean warming must continue to be a high priority. Nonetheless, several gaps remain in measuring, estimating and understanding ocean warming.

First, the current ocean observing system needs to be sustained and extended to monitor OHC change at various spatiotemporal scales. The critical question of ‘how adequate is the ocean observing system for monitoring the OHC changes at various timescales?’ is still not fully answered. The international community have cast their eyes toward the future to improve not only the Argo fleet but also other measurement methodologies259,260,261. The ongoing and planned efforts include the maintenance of the current GOOS, and shipboard in situ measurements for calibration, validation and quality control of the Argo array; a drive toward spatial completion, including polar sea-ice zones, marginal seas and complicated channels; increased resolution in critical areas such as boundary currents and coastal areas; incorporation of deeper measurements (for example below 2,000 m); and inclusion of biological and chemical signals, along with temperature and salinity (Deep Argo and BioGeoChemical Argo programmes). The scientific community and funding agencies will need to be mindful of ensuring a continuous and comprehensive measurement network for the world’s ocean — a network that incorporates new technologies as they are developed and retires old technologies that have outlived their usefulness, but with a good understanding of the handoff between technologies.

Second, uncertainty for OHC estimate needs to be better understood and quantified. In addition to data coverage, uncertainty also stems from mapping methods associated with data sampling, instrumental bias correction, choice of climatology, quality-control and other data processing procedures. These error sources are not independent of each other and are likely to lead to biases in current analyses. Thus, uncertainty in OHC estimate is method-dependent and producer-dependent. The contribution of each error source to the total OHC uncertainty is not fully understood, and the error range given by different datasets results in roughly 10-fold differences33. New approaches can be used to better quantify the uncertainty: for example, synthetic data for understanding and evaluating the mapping method, and exploiting ensembles (applying different techniques and forming an ensemble of OHC estimates)59,262,263,264.

Third, syntheses of multisource (direct and indirect) observations and models are recommended to improve OHC estimates and mechanistic understanding. Synthesis of in situ observations with satellite-based observations (sea level altimetry, ocean colour, surface wind stress) and full atmospheric analyses shows the most promise. The indirect datasets can either serve as a cross-evaluation tool or constrain direct estimates, such as closing energy, water and sea level budgets. Attempts show promising results. As a coupled system, the separate impacts of atmospheric, ocean and ice (and other components) dynamics cannot be easily isolated265, and identifying the coupling mechanism driving OHC patterns remains a high research priority. Capabilities for integrating different sources of Earth system observations and information (for example, model-based data assimilation and simulations) for a comprehensive quantification of the energy budgets should be built. For example, the integration of atmospheric and oceanic data leads to a quantification of MHT time series at all latitudes, capable of resolving interannual variability133.

Fourth, the current generation of climate and Earth system models still contain non-negligible uncertainties in representing past and future ocean warming trends202,205,212. For example, there is substantial uncertainty in CMIP6 future projections in the Antarctic margin region, due to biases in simulated stratification158, hydrography around the Antarctic shelf 266, and missing processes, including eddies, tides, ice-shelf cavities, and ocean–ice-shelf interactions. In the tropics, it is known that tropical cyclones mix the ocean through substantial depths. Moreover, they form in hot spots and cool the ocean, yet they are largely absent from global models. In addition, interannual to decadal variability such as ENSO and the IPO remains poorly represented in modern-day climate models, yet they strongly control the pattern and timing of OHC anomalies. As ocean and atmospheric circulation have a key role in shaping the climate response (including ocean warming pattern and OHU efficiency)127,203, evaluating the accuracy of the wind, atmosphere and ocean circulation projections should continue to be a research priority. A continuous process-based understanding of model performance is recommended including the understanding and identification of persistent biases in simulations, especially with respect to the diagnostics for Earth’s major system cycles.

Fifth, understanding of extreme OHC events, their compound effects and past changes in OHC should be strengthened. For example, MHWs have been identified from surface conditions, but subsurface components are also important, and OHC as an indicator offers a way to integrate these aspects. The simultaneous occurrence of ocean warming extremes with other extremes (deoxygenation, acidification) requires special attention236. A more complete understanding of OHC changes in the deep past before the widespread availability of instrumental records is also critical to put the current changes in the context of a longer timescale267. Research on past climate change also helps us to understand how natural drivers and human influence have changed the Earth’s climate system. The difficulty is a lack of full-depth temperature proxy data. Several methods have been developed to derive OHC change back to the past 20,000 years (Last Glacial Maximum), but the uncertainty is large95,268.

More articles on Flood Insurance, Extreme Weather Events and Global Warming.

bookmark_borderLong-COVID: 4 Out of 5 Experiencing Limitations in Daily Activities

The CDC Panel Report Long COVID Panel Survey found:

* 81% of adults with ongoing symptoms of COVID lasting three months or longer — or four out of five adults — are experiencing limitations in their daily activities compared to before they had the virus. (Economic implications include work force participation and long-term health care costs.)

* Young adults between ages 18 and 29 had the highest share of people currently with long COVID who have trouble performing daily tasks, at 86.3%. What will the long-term costs and quality of life be when these people are in their 50’s,60’s, and if they get to live into their 70’s?

Long-COVID Survey
Long-COVID Survey

COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderClimate Change: Increasingly Costly for Americans to Insure Their Homes

The report by PolicyGenius Home insurance prices are rising even faster than inflation explains how climate change is making homeowners’ insurance more difficult and costly to obtain:

Severe natural disasters
Climate change has increased both the length and severity of the hurricane and wildfire seasons in the U.S., causing many insurance companies to increase rates or stop offering coverage in high-risk areas altogether. When there’s fewer companies doing business in a particular area, the ones left are forced to establish stricter underwriting rules and increase rates on new and existing customers.

Record catastrophe losses
There were 97 natural disasters resulting in $92 billion in insured losses in 2021, according to the Insurance Information Institute (III). This is up from 92 events totaling $74 billion in losses in 2020. As a result, insurers have had to increase rates to account for higher reconstruction costs in affected areas, and to make up for the record losses.

Without decisive action to mitigate climate change, frequent droughts will threaten jobs and agricultural yields in Oklahoma and Texas; extreme heat will devastate an already high proportion of vulnerable residents in Mississippi and Kentucky; and the number of homes with flood risk will increase significantly in Louisiana and Delaware, according to our 2021 Policygenius Best & Worst States for Climate Change Index.

Last October, FEMA revamped its program to more accurately assess flood risk, causing insurance premiums for some coastal properties to rise to $4,000 or $5,000 annually, up from just $700 or $800, Porter from First Street Foundation said.

These hikes may be prohibitively expensive for lower-income families or retirees, especially those who may be living in a property inherited from family, Wright said.

“These family houses have been around forever, and they may not have a mortgage, so flood insurance may not be required,” he said. “But they should have it anyway.”

More articles on Flood Insurance, Extreme Weather Events and Global Warming.

bookmark_borderRapidly Increasing Disasters, Costs, and Frequency

The rapid increase in disaster costs and frequency in the USA is the focus of the report by Climate Central Billion-Dollar Disasters in 2022.

The report states:
* As of this month, the U.S. has experienced 15 billion-dollar weather and climate disasters so far in 2022—already well above the historical average of seven events per year.

* This year’s mounting extreme weather costs reflect an increasing trend in U.S. billion-dollar disasters since 1980.

* The frequency of billion-dollar disasters has also increased. In the last five years (2017-2021), there were just 18 days on average between billion-dollar disasters—compared to 82 days in the 1980s.

* Less time between disasters can mean less time and resources available to respond, recover and prepare for future events.

* The full toll of such events—including the impacts on health—can’t be captured in any one statistic. Without rapid cuts in heat-trapping emissions, this toll is likely to keep rising.

Billion-dollar disasters in 2022

The devastation wrought by Hurricanes Fiona and Ian in Puerto Rico, Florida, and beyond has once again thrust weather and climate disasters to the forefront of the nation’s attention.

According to NOAA, the U.S. has experienced 15 weather and climate disasters with losses exceeding $1 billion each in 2022 (as of September 30). The total cost of these disasters through the end of September was $29.3 billion. Adding up the final costs will take months after the end of the year to complete.

The costly and deadly billion-dollar disasters of 2022 so far have included:

* an April tornado outbreak in the Southeast that spawned 88 tornadoes, including several intense, long tracked tornadoes in Georgia and South Carolina

* a May hail storm that left large swaths of golf-ball sized hail across Minnesota, Wisconsin and South Dakota

* a destructive derecho that produced widespread 70+ mph wind gusts across the lower Midwest

* The costs of Hurricane Fiona and Hurricane Ian are still being accounted for as ongoing recovery continues. Historically, hurricanes and tropical cyclones are the most costly disasters by far, averaging $21 billion per event—more than double the average toll of the next most costly event type (drought).

More Disasters

This year’s mounting extreme weather costs reflect an increasing trend in billion-dollar disasters across the U.S. Each decade since the 1980s has experienced more billion-dollar disasters and higher costs than the decade before.

Over the last five years (2017 to 2021) alone, a total of 89 events caused an estimated 4,557 deaths and over $788 billion dollars in damage. That’s about 35% of the $2.27 trillion in total costs of U.S. billion-dollar disasters from 1980-2021.

2022 is the eighth consecutive year with 10 or more billion-dollar weather and climate-related disasters. The long-term (1980–2021) annual average is about seven billion-dollar disasters per year. And 2022 follows the record-shattering annual totals of 22 and 20 billion-dollar disasters in 2020 and 2021, respectively.

More Often

It’s not just the total number of disasters—but how often they occur—that strains the resources available for communities to manage risks and recover quickly.

Between 1980-2021, the time between billion-dollar disasters in a calendar year has dropped steadily, according to an analysis by Climate Central.

* The average time between billion-dollar disasters has dropped from 82 days in the 1980s to 26 days in the 2010s.

* In the last five years (2017-2021), there have been just 18 days on average between billion-dollar disasters.

* During 2020, there were as little as two weeks on average between the record 22 billion-dollar disasters that year.

Less time between disasters can mean less time and resources available to respond, recover and prepare for future events.

The highest costs have resulted when multiple disasters occur in the same region and season, straining local resources—as during the Atlantic hurricane seasons of 2005 and 2017. According to NOAA, multiple billion-dollar tropical cyclones during these two seasons resulted in more than 5,000 lives lost and over $520 billion in combined damages.
The full toll of disasters

These staggering figures primarily reflect direct impacts on assets (including damage to homes, crops, and critical infrastructure), and therefore don’t reflect the full toll of disasters, including on public health—and especially mental health. According to the American Public Health Association, up to 54% of adults and 45% of children suffer depression after a disaster.

Weather and climate-related disasters can also result in widespread power outages (as occurred in Puerto Rico after Hurricane Fiona), displacement, and limited or unsafe food and water supplies, as well as loss of cultural heritage, biodiversity and habitats.

These figures also don’t convey the disproportionate impacts of disasters on people in poverty or the need for equitable allocation of federal disaster assistance in accordance with social vulnerability.
Disasters in a warming world

According to the latest IPCC reports, it is an “established fact” that human-caused greenhouse gas emissions have “led to an increased frequency and/or intensity of some weather and climate extremes since pre-industrial times.” And these trends are projected to continue with additional warming.

The ambition of the Paris Agreement—to limit warming to 2.7°F (1.5 °C) by 2100—is very likely to be exceeded by the mid-2040s at the latest without rapid emissions cuts. In November, nearly 200 nations will convene at the United Nations Climate Change Conference (COP27) to accelerate climate action. Without such progress, we can expect even more frequent and intense billion-dollar disasters in the future.

More articles on Extreme Weather Events and Global Warming.

bookmark_border10% of Canadian Homes Uninsurable Due to Extreme Weather and the Climate Crisis

The Guardian reports The uninsurables: how storms and rising seas are making coastlines unliveable.

“In Canada, the number of uninsurable homes has reached 10%, according to industry figures. The Magdalen archipelago is losing half a metre each year to erosion, roads have fallen into the sea and the sand dunes that once offered protection from squalls are disappearing faster than they can be saved, but it is not just there. Most of Canada’s major cities are built on the frontlines of a changing climate – along rivers and coastlines or on flood plains.”

“Over the past 15 years, insurance claims from severe weather events in Canada – windstorms, flooding, wildfire and drought – have more than quadrupled. Seven of the country’s costliest disasters occurred in the last decade. Insurers now expect to disburse C$2bn (£1.3bn) in disaster-related payouts annually, with costs only expected to rise.”

“A federally run fund, meant to help communities build disaster-resilient infrastructure, is quickly running out of money years before it expires at the end of the decade. It has already received far more requests than it can pay for, and despite the federal government repeatedly topping it up, more than half of the money has been spent.”

“Without any sort of concerted effort or gameplan, that figure will only grow. We’re continuing to build in harm’s way, largely on water, because that’s where people love to be. And the modelling shows that these storm events are just going to become more frequent and more intense in the years ahead,” says Craig Stewart, vice-president of the IBC’s climate change and federal issues portfolio. “The risk is growing. And so far, our efforts at risk reduction have been terrible.”

“The private market, on its own, cannot handle the level of risk that’s escalating in the system without some sort of formal government backstop or direct participation.”

In the US, Florida has blocked insurers from withdrawing from the market for at least two months after Hurricane Ian. Officials in the US have also warned residents about the dangers of rebuilding in areas likely to suffer weather-related disasters.

In November 2021, a powerful “atmospheric river”, a plume of water-laden air, led to widespread flooding in the province of British Columbia. Highways and bridges were washed away and thousands of homes – built on an old lake bed that was a known flood plain – were submerged in turbid waters. The damage cost insurers nearly C$675m – with billions more in uninsured costs having to be borne by residents and government.

The floods also hit the town of Lytton, British Columbia, which a few months earlier had been the site of scorching temperatures before it was all but destroyed by a wildfire. In the aftermath, the uncertainty of how to rebuild – or whether to rebuild – has become a flashpoint.

“There was conflict between people who wanted to rebuild Lytton better, and those who were traumatised by the fire and they wanted to put their lives back together as quickly as possible without any change,” says Porter. “They didn’t want to be told what to do. They didn’t want outsiders coming in and telling them you must change your life in such a way.”

Governments are bracing for the mounting costs from extreme weather to upend life in cities. A recent report warned that floods and droughts could cost the global economy US$5.6tn by 2050.

More articles on Flood Insurance, Extreme Weather Events and Global Warming.

bookmark_borderLong-COVID: reduced exercise capacity and muscle cell death

A symptom of long COVID may be the reason you feel exhausted after a workout — “long COVID may reduce exercise capacity, measured by how much oxygen your body can use and how your heart and lungs function during exercise.”

In January of 2024, a study found long-COVID patients have muscle abnormalities that resulted in cell death after exercise. “It’s really confirming that there is something inside the body going wrong with the disease,” said Dr Rob Wüst, an author of the study at Vrije Universiteit (Free University) Amsterdam.

In the report Cardiopulmonary Long COVID-19 Symptoms found “exercise capacity was reduced by 4.9 mL/kg/min among individuals with symptoms consistent with LC compared with individuals without symptoms more than 3 months after SARS-CoV-2 infection. Findings among individuals with exertional intolerance suggest that deconditioning, dysfunctional breathing, chronotropic incompetence, and abnormal peripheral oxygen extraction and/or use may contribute to reduced exercise capacity.”

“This decline in oxygen peak rate would roughly translate to a 40-year-old woman with an expected exercise capacity of 9.5 METs, dropping to 8.1 METs, the approximate expected exercise capacity for a 50-year-old woman,” says Dr. Matt Durstenfeld, an author on the study and assistant professor of medicine at the University of California, San Francisco.

The press release “Feeling winded after your workout? Long COVID may claim another symptom” states:
The findings suggest that the long COVID cohort in this subgroup may have reduced oxygen extraction in the muscles, irregular breathing patterns, and a lesser ability to increase heart rate during exercise to match cardiac output. In addition, there was evidence of deconditioning, which occurs to some extent after most physical illnesses that result in inactivity, the researchers noted. Importantly, not all the findings could be attributed to deconditioning.

Exercise tests were conducted at least three months following SARS-CoV-2 infection and involved cardiopulmonary exercise testing (CPET), in which oxygen and carbon dioxide were measured, together with other indices of heart and lung function, while the participant used a treadmill or stationary bike.

Doubles Tennis, Lap Swims May Be Too Strenuous for Those With Long COVID

In comparing exercise tolerance, the researchers found the long COVID group’s peak rate of oxygen was 4.9 ml/kg/min lower than the recovered group. According to first author Matthew S. Durstenfeld, MD, MAS, of the UCSF Department of Medicine and of the Division of Cardiology at Zuckerberg San Francisco General Hospital, this difference is equivalent to 1.4 metabolic equivalent of tasks (METs), a measure of energy consumed during physical activities. “This decline in oxygen peak rate would roughly translate to a 40-year-old woman with an expected exercise capacity of 9.5 METs, dropping to 8.1 METs, the approximate expected exercise capacity for a 50-year-old woman,” he said.

Another way of looking at it, Durstenfeld said, is that a doubles tennis player might need to transition to playing golf with a cart or stretching exercises, and those who swim laps may find that low-impact aerobics is a better match.

The study Muscle abnormalities worsen after post-exertional malaise in long COVID found exercise causes the destruction of muscle cells.

A distinctive symptom of patients with long COVID is post-exertional malaise (malaise is a general feeling of discomfort, illness, or uneasiness whose exact cause is difficult to identify), which is associated with a worsening of fatigue and pain-related symptoms after acute mental or physical exercise, but its underlying pathophysiology is unclear. We show that skeletal muscle structure is associated with a lower exercise capacity in patients, and local and systemic metabolic disturbances, severe exercise-induced myopathy and tissue infiltration of amyloid-containing deposits in skeletal muscles of patients with long COVID worsen after induction of post-exertional malaise.

Patients with long COVID displayed a markedly lower exercise capacity, which related to skeletal muscle metabolic alterations and a shift towards more fast-fatigable fibers. The pathophysiology of post-exertional malaise includes an acute exercise-induced reduction in skeletal muscle mitochondrial enzyme activity, an increased accumulation of amyloid-containing deposits in skeletal muscle, signs of severe muscle tissue damage, together with a blunted exercise-induced T-cell response in skeletal muscle. Collectively, these findings help to decipher the underlying physiology of fatigue and a limited exercise capacity from the development of post-exertional malaise in patients with long COVID.

Viral infections can alter mitochondrial function, and multiple studies have shown that residual SARS-CoV-2 protein presence is associated with long COVID. It is unknown if the full virus is present, or only protein remnants. Because the spike protein is located on the exterior of the virus, this protein may have different proinflammatory/coagulatory effects compared with the nucleocapsid protein. The higher skeletal muscle infiltration of CD68+ macrophages and CD3+ T-cells suggests a locally disturbed immune response in patients with long COVID.

In conclusion, this study reveals that local and systemic metabolic disturbances, severe exercise-induced myopathy, infiltration of amyloid-containing deposits, and immune cells in skeletal muscles of long COVID are key characteristics of post-exertional malaise. While these explain the symptomatology of post-exertional malaise in long COVID, the molecular pathways underlying these alterations in patients suffering from post-exertional malaise remain to be determined.

COVID-19 / SARS-CoV-2 / Novel Coronavirus

bookmark_borderThe Collapse of Nature

The World Wildlife Foundation issued a report LIVING PLANET REPORT 2022 showing a near 70% decline in wildlife.

* Monitored populations of vertebrates (mammals, birds, amphibians, reptiles and fish) have seen a devastating 69% drop on average since 1970

* Freshwater species populations have suffered an 83% fall

* The report’s Living Planet Index shows that there is no time to lose in securing a nature-positive society

* Deforestation, human exploitation, pollution, and climate change were the biggest drivers of the loss

Many scientists believe we are living through the sixth mass extinction – the largest loss of life on Earth since the time of the dinosaurs – and that it is being driven by humans.

Tanya Steele, chief executive at WWF-UK, said: “This report tells us that the worst declines are in the Latin America region, home to the world’s largest rainforest, the Amazon. Deforestation rates there are accelerating, stripping this unique ecosystem not just of trees but of the wildlife that depends on them and of the Amazon’s ability to act as one of our greatest allies in the fight against climate change.”

“Despite the science, the catastrophic projections, the impassioned speeches and promises, the burning forests, submerged countries, record temperatures and displaced millions, world leaders continue to sit back and watch our world burn in front of our eyes,” said Steele. “The climate and nature crises, their fates entwined, are not some faraway threat our grandchildren will solve with still-to-be-discovered technology.”

She added: “We need our new prime minister to show the UK is serious about helping people, nature and the economy to thrive, by ensuring every promise for our world is kept. Falling short will be neither forgotten nor forgiven.”

The Human Induced Climate Change Experiment

bookmark_borderHeat Waves Make Regions Uninhabitable Within Decades

The U.N. humanitarian aid agency OCHA and the International Federation of Red Cross report Extreme heat: Preparing for the heatwaves of the future (October 2022) says large parts of the earth will become uninhabitable in the near future.

“We don’t want to dramatize it, but clearly the data shows that it does lead towards a very bleak future,” said IFRC secretary-general Jagan Chapagain.

There are clear limits beyond which people exposed to extreme heat and humidity cannot survive. There are also likely to be levels of extreme heat beyond which societies may find it practically impossible to deliver effective adaptation for all. On current trajectories, heat waves could meet and exceed these physiological and social limits in the coming decades, including in regions such as the Sahel and south and southwest Asia.

Projected future death rates from extreme heat are staggeringly high — comparable in magnitude by the end of the century to all cancers or all infectious diseases — and staggeringly unequal.

If emissions of the greenhouse gases which cause climate change are not aggressively reduced, the world will face “previously unimaginable levels of extreme heat”.

The Human Induced Climate Change Experiment

bookmark_borderHurricane Ian: Florida Becoming Uninhabitable

October 2, 2022

How long would it take to go 100% green?
“It depends on cooperation. If we all cooperated, we could change over within 6 months. However, we don’t expect the climate deniers will cooperate. In the meantime, many countries plan to reduce fossil fuels by 2030. Some countries, such as China, are building nuclear plants. The UK will transition from natural gas to green hydrogen with most of the regulations in place by 2030.”

“The key to how fast the US transitions is in the cost to ourselves (since we don’t seem to care about the rest of the world.) This can already be seen in Florida and Louisiana where almost all of the homeowners/hazard insurance companies have pulled out. FEMA is a good place to focus our forecasts. FEMA’s flood insurance is the only government subsidized insurance available to everybody. When the government stops subsidizing extreme weather events, you will see an instant turnover to 100% green. The intensity and frequency of extreme weather events is growing exponentially; therefore, we expect FEMA will be bankrupted in short order. At that time, much of US real estate will become worthless and the cost of burning fossil fuels will be deemed too costly. The people impacted by financial and life losses will litigate the fossil fuel industry out-of-business,” said climate scientist Daniel Brouse.

The Costs of Climate Change
Hurricane Ian will be one of the most costly disasters on record, both in terms of money and lives. Over 2 million people lost power. Roads and bridges were destroyed. Some inhabited islands literally got washed away. The hurricane was so powerful that it is difficult to calculate the number of deaths as the bodies can not be found.

The Insurance Journal reports:
Wind and storm-surge losses from Hurricane Ian could reach as $47 billion in Florida alone, a figure made larger by inflation and rising interest rates, the property analytics firm CoreLogic said in a new analysis.

“This is the costliest Florida storm since Hurricane Andrew made landfall in 1992 and a record number of homes and properties were lost due to Hurricane Ian’s intense and destructive characteristics,” said Tom Larsen, associate vice president for hazard and risk management at CoreLogic.

“Hurricane Ian will forever change the real estate industry and city infrastructure,” Larsen said in a news release. “Insurers will go into bankruptcy, homeowners will be forced into delinquency and insurance will become less accessible in regions like Florida.”

More articles on Flood Insurance, Rising Sea Levels and Global Warming.

bookmark_borderCOVID-19 Significantly Higher Risk of Alzheimer’s

The risk of older people (over 65) developing Alzheimer’s disease over a one-year period nearly doubled following a COVID-19 diagnosis. The same researchers had previously found that individuals with dementia had a greater risk of contracting COVID-19 and being hospitalized and dying from the disease than those without dementia.

“Many people believe that for Alzheimer’s disease there is a combination of factors that work together to give you the cognitive impairment, and we were concerned that the kinds of things that happened during COVID-19 — the intense inflammation, and perhaps the kinds of direct action on the brain of the of the virus — might be a risk factor,” Dr. Davis, the study’s co-author, said. “So we went looking for that in our study.”

“We can say that they are associated, but we cannot infer causality,” she stressed.

“First, the pandemic presented serious delays for individuals seeking out medical diagnoses like Alzheimer’s disease, meaning these results could be driven by those who already had Alzheimer’s disease when they were infected but had not yet sought out a formal diagnosis,” Dr. Snyder, vice president of medical and scientific relations at the Alzheimer’s Association, explained.

“Alternatively, COVID-19 infection — which is linked to immune changes, including inflammation — may impact the onset of brain changes that are linked to Alzheimer’s disease and other dementia,” said Dr. Snyder. “However, because this study only showed an association through medical records, we cannot know what the underlying mechanisms driving this association are without more research.”

Association of COVID-19 with New-Onset Alzheimer’s Disease

COVID-19 / SARS-CoV-2 / Novel Coronavirus