“Reprogramming of host metabolism supports viral pathogenesis by fueling viral proliferation, by providing, for example, free amino acids and fatty acids as building blocks,” as reported in COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status. “Targeted and untargeted metabolomics analyses identified altered tryptophan metabolism into the kynurenine pathway, […]
Category Archives: health and wellness
COVID-19 and Tryptophan Deficiency
COVID depletes your NAD+. The body hijacks tryptophan trying to make NAD+. This is one cause of post-COVID anxiety. There are other causes of post-COVID low tryptophan levels. “Low serum and muscle tryptophan levels, as well as elevated kynurenine levels, may be to blame for COVID-19’s most common long-term symptoms, such as depression, sleep disturbances, […]
COVID-19: Chronic Conditions
By Daniel Brouse help@membrane.com “I describe it as a bit like somebody throwing a hand grenade into our immune system, that all the populations [of immune cells] are completely topsy turvy and unsettled for years. And, that’s a guess, but we’ve got the technology to look at that in quite a lot of detail,” said […]
COVID: The Natural Immunity Myth
by Daniel Brouse August 30, 2021 To date, there is zero (0) evidence that contracting the original strain of COVID gives you any immunity to re-infection — natural immunity. On the other hand, there are a multitude of examples of re-infection. Natural immunity to the original strain lasts on average from 60 days to 6 […]
Long-COVID: What We Know About Long Haulers Syndrome
by Daniel Brouse August 25, 2021 help@membrane.com Post Acute Covid Syndrome 19 (PACS19), long-COVID, and Long Haulers Syndrome are names for the condition that an individual has after recovering from the SARS-CoV-2 virus. Long-COVID is actually a combination of several conditions and syndromes including changes to your genetics, an accelerant to aging, and the persistence […]
COVID Vaccine Breakthrough Cases
by Daniel Brouse August 23, 2021 help@membrane.com Q: Why are there so many breakthrough cases of COVID in the vaccinated? A: There are several reasons why there are breakthrough cases with any vaccine; however, COVID is different. Many of the vaccinated people getting COVID already had COVID prior to being vaccinated. This is the second […]
COVID-19 Delta Variant and Vaccines
By Daniel Brouse What do we know about the Delta variant and vaccines? OVERVIEW The efficacy of mRna vaccines is about 79% against contracting the Delta variant. Non-mRna vaccines are between 40-60% effective against Delta. Vaccines lose efficacy at about 3%/month after six months of being fully vaccinated. Vaccines appear to help contain the Delta […]
Long-COVID and Environmental Aggravators
by Daniel Brouse help@membrane.com Exercise aggravates long-COVID symptoms. COVID causes changes to your genes making it harder to create NAD+ and quicker to consume NAD+. Normally, exercise helps boost your NAD+. Not with long-COVID. The inflammation caused by exercise, anxiety, or exertion causes a rapid depletion of NAD+ aggravating long-COVID symptoms and perpetuating the downward […]
Post-Acute COVID-19 — COVID Long Haulers Syndrome
Guy A. Richards1, Adrian Wentzel2, Robert Miller COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity Wentzel, Miller, Richards COVID-19: NAD+ Deficiency by Wentzel, Miller, Richards (PDF) Treatment of SARS-CoV-2 induced pneumonia with NAD+ in a mouse model Jiang, Deng, Ma, Pang, Hu, Qin, […]